Tetrahydrocannabivarin (THCV)

Image via Medical Jane

Image via Medical Jane

What Is Tetrahydrocannabivarin (THCV)?

As the name might suggest, tetrahydrocannabivarin (THCV) is very similar to the most famous cannabinoid, tetrahydrocannabinol (THC); THCV is like THC’s propyl cannabinoid cousin. Their chemical structure is nearly identical, but the process involved in their creation is slightly different.

Unlike THC, cannabidiol (CBD), and cannabichromene (CBC), THCV doesn’t begin ascannabigerolic acid (CBGA). Instead of combining with olivetolic acid to create CBGA, the geranyl phosphate joins forces with divarinolic acid, which has 2 less carbon molecules. The result is cannabigerovarin acid (CBGVA).

Once CBGVA is created, the process continues exactly same as it would for THC. CBGVA is broken down to tetrahydrocannabivarin carboxylic acid (THCVA) by the THCV synthase. At that point, THCVA can be decarboxylated with heat or UV light to create THCV.

The Benefits Of THCV

The relationship between THC and THCV is obvious in the effects as well. Although both cannabinoids effect the same receptors, they do so in a different manner. THCV is actually an antagonist of the CB1 and CB2 receptors, and is being studied for its use as an appetite suppressant.

THCV helps curb your appetite. It is likely one of the reasons why cannabis users are slimmer on average.

Researchers have already found a relation between theendocannabinoids and appetite. Expanding on these findings, they are interested in the potential forTHCV to aid in fighting obesity. It’s believed that it blocks the rewarding sensations we experience when eating, often unhealthy, comfort foods.

Not only can THCV help you fit into that new pair of jeans, but it also has anti-convulsive properties. THCV seems to lower the seizure threshold for those with epilepsy. As a result, they experience less seizures.

Article via Medical Jane

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